11/30/2022 0 Comments New world disorder 9 torrentTo the best of our knowledge, this is the first randomized controlled trial to compare functional remediation with a psychoeducational intervention and treatment as usual. This therapy involves neurocognitive techniques, training, psychoeducation on cognition-related issues, and problem-solving within an ecological framework ( 9), in an approach that attempts to avoid the problems with generalizability of learning that occurred in several cognitive remediation studies in schizophrenia. In the present study, we sought to assess the efficacy of functional remediation, a neurocognitive intervention designed specifically for bipolar patients. It found that 18 bipolar patients with residual depressive symptoms improved both symptomatically and in their psychosocial functioning. To our knowledge, only one study ( 12), using an open-label design, has actually focused on bipolar patients. Until recently, cognitive remediation strategies were regarded primarily as an intervention for schizophrenia ( 11), but little is known about neurocognitive remediation in affective disorders ( 12– 17). Given the impact of neurocognitive impairment on daily functioning ( 6– 8), there is a need to develop adjunctive therapies that target neurocognitive skills in order to enhance everyday functioning ( 9, 10). In recent years, functional outcome has become an issue of major concern not only in clinical settings but also because it represents a social and economic burden for society ( 5). Moreover, neurocognitive deficits, together with other clinical and sociodemographic factors, are thought to contribute to functional impairment ( 3, 4). In fact, it is estimated that only one-third of patients achieve full social and occupational recovery and return to their premorbid functional levels. These rates are quite similar to those reported for functional impairment. It is well established that 40% to 60% of patients with bipolar disorder experience neurocognitive impairment not only during acute mood episodes but also during euthymic periods ( 1, 2). New Research Full Access Efficacy of Functional Remediation in Bipolar Disorder: A Multicenter Randomized Controlled Study
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